Soft Tissue Sarcoma. malignant phyllodes tumor of the breast were followed up at 3 monthly intervals. Additionally, they recommend cautious use of radiotherapy, particularly in young patients. Current guidelines for phyllodes tumor recommend against axillary dissection and chemotherapy use. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Breast Cancer include up-to-date recommendations for the clinical management of patients with carcinoma in situ, invasive breast cancer, Paget disease, phyllodes tumor, inflammatory breast cancer, and breast cancer … The National Comprehensive Cancer Network (NCCN ) makes no representations or Malignant phyllodes tumors: a review of 752 cases. Version 2.2016. These are rare breast tumors that start in the connective (stromal) tissue of the breast. Updates in Version 1.2019 of the NCCN Guidelines for Breast Cancer from Version 4.2018 include: Continued UPDATES General: Recommendations for Lobular Carcinoma in Situ (LCIS-1) were removed from the NCCN Guidelines for Breast Cancer; see the NCCN Guidelines for Breast Cancer Screening and Diagnosis. NCCN Clinical practice guidelines in oncology (NCCN Guidelines). Those with an associated invasive cancer should undergo adjuvant systemic therapy based on the stage and hormone receptor status, as outlined online, in these guidelines, at www.NCCN.org . Locally recurrent breast mass following excision of phyllodes tumor Metastatic disease 1 Pathology should be reviewed to assess for fibroadenoma versus phyllodes (phyllodes benign, borderline and malignant). According to NCCN guidelines wide excision means excision with the intention of obtaining surgical margins ≥1 cm. National Comprehensive Cancer Network (NCCN). Exact extent of clearance under debate, currently no consensus as to adequate margin width, while 10 mm is generally considered acceptable (NCCN Guidelines: Breast Cancer - Phyllodes Tumor [Accessed 2 July 2020], Ann Surg Oncol 2019;26:2747) Axillary dissection not indicated Phyllodes tumors are most common in women in their 40s, but women of any age can have them. This follows the same breast cancer follow up protocol defined by NCCN guidelines. Without prospective trials to guide management, NCCN also recommends consideration of radiation therapy (XRT). Phyllodes tumors (FILL-odes or full-OH-deez) can also be spelled phylloides tumors (full-OY-deez). NCCN Guidelines for the Management of Phyllodes Tumor. Grabowski J, Salzstein SL, Sadler GR, Blair SL. Available at: www.nccn.org (Accessed on February 22, 2016). DCIS-1 INTRODUCTION: National Comprehensive Cancer Network (NCCN) guidelines recommend wide excision without axillary staging to treat phyllodes tumors of the breast. 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